Company Filing History:
Years Active: 2006
Title: Vince A. Chiodo: Innovating in Gene Therapy through Pseudotyped Recombinant AAV Virions
Introduction: Vince A. Chiodo, based in Gainesville, Florida, has made significant strides in the field of gene therapy. With a focused expertise that culminated in one patented innovation, he is recognized for his contributions toward advancing viral vector technology.
Latest Patents: His notable patent, titled "Production of pseudotyped recombinant AAV virions," showcases a groundbreaking method for creating vectors that encode Adeno-Associated Virus (AAV) Rep and Cap proteins from different serotypes, along with Adenovirus transcription products. These vectors facilitate the production of pseudotyped recombinant AAV (rAAV) virions. Remarkably, the purification methods developed yield rAAV stocks that are 99% pure, with titers of 1×10–1×10 vector genomes/ml, highlighting the efficiency and effectiveness of his methods.
Career Highlights: Vince Chiodo is affiliated with the University of Florida Research Foundation, Incorporated, where he has contributed to pioneering research in viral gene delivery systems. His work aligns closely with contemporary needs in gene therapy, fostering innovations that may one day empower treatments for genetic disorders.
Collaborations: Throughout his career, Chiodo has collaborated with esteemed coworkers such as Richard O. Snyder and Sergei Zolotukhin. These partnerships illustrate the collective effort required in research and the vital role of teamwork in achieving significant scientific breakthroughs.
Conclusion: Vince A. Chiodo's patent and research endeavors represent a vital contribution to gene therapy. By enhancing the production of pseudotyped recombinant AAV virions, he is paving the way for future innovations that could transform therapeutic strategies for various diseases. His work at the University of Florida Research Foundation exemplifies the intersection of academic research and practical application, contributing significantly to advancements in biotechnology.