The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2006

Filed:

Mar. 11, 2004
Applicants:

Richard O. Snyder, Gainesville, FL (US);

Sergei Zolotukhin, Gainesville, FL (US);

Yoshihisa Sakai, Gainesville, FL (US);

Barry J. Byrne, Gainesville, FL (US);

Mark R. Potter, Gainesville, FL (US);

Irine Zolotukhin, Gainesville, FL (US);

Scott Loiler, Gainesville, FL (US);

Vince A. Chiodo, Gainesville, FL (US);

Nicholas Muzyczka, Gainesville, FL (US);

William W. Hauswirth, Gainesville, FL (US);

Terence R. Flotte, Alachua, FL (US);

Corinna Burger, Gainesville, FL (US);

Edgardo Rodriguez, Gainesville, FL (US);

Kevin R. Nash, Gainesville, FL (US);

Thomas J. Fraites, Gainesville, FL (US);

Inventors:

Richard O. Snyder, Gainesville, FL (US);

Sergei Zolotukhin, Gainesville, FL (US);

Yoshihisa Sakai, Gainesville, FL (US);

Barry J. Byrne, Gainesville, FL (US);

Mark R. Potter, Gainesville, FL (US);

Irine Zolotukhin, Gainesville, FL (US);

Scott Loiler, Gainesville, FL (US);

Vince A. Chiodo, Gainesville, FL (US);

Nicholas Muzyczka, Gainesville, FL (US);

William W. Hauswirth, Gainesville, FL (US);

Terence R. Flotte, Alachua, FL (US);

Corinna Burger, Gainesville, FL (US);

Edgardo Rodriguez, Gainesville, FL (US);

Kevin R. Nash, Gainesville, FL (US);

Thomas J. Fraites, Gainesville, FL (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/10 (2006.01); C12N 15/864 (2006.01); C12N 15/35 (2006.01);
U.S. Cl.
CPC ...
Abstract

Vectors that encode Adeno-Associated Virus (AAV) Rep and Cap proteins of different serotypes and Adenovirus transcription products that provide helper functions were used to produce pseudotyped recombinant AAV (rAAV) virions. Purification methods generated pseudotyped rAAV virion stocks that were 99% pure with titers of 1×10–1×10vector genomes/ml.


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