Company Filing History:
Years Active: 2022-2023
Title: **Vassilios Kalabokis: Innovator in Immune Checkpoint Modulation**
Introduction
Vassilios Kalabokis, based in Fridley, MN, is a notable inventor with a focus on modulating immune responses. With three patents to his name, his work has the potential to impact the fields of immunotherapy and cancer treatment significantly.
Latest Patents
Kalabokis' recent inventions include compounds that modulate the interaction of VISTA and VSIG3, along with methods for their development and application. His patented technologies describe the creation of polyclonal and monoclonal antibodies that specifically bind to VSIG3. These inventions lay the groundwork for innovative methods that influence the interaction between VISTA and VSIG3, providing a pathway for therapeutic advancements in immunotherapy. Furthermore, his work identifies VSIG3/VISTA as a novel immune checkpoint, highlighting the potential use of these interactions for developing agonist or antagonist compounds, including antibodies and fusion proteins. Such compounds aim to either suppress VSIG3/VISTA's effects on T cell immunity in cancer treatment or enhance these effects in conditions like autoimmunity and allergies.
Career Highlights
Kalabokis has contributed his expertise to prominent organizations, including Bio-Techne Corporation and the University of Colorado. His experiences in these leading institutions have influenced his research and innovation trajectory, positioning him as a key player in his field.
Collaborations
Throughout his career, Kalabokis has collaborated with talented individuals such as Jinghua Wang and Guoping Wu. These collaborations have likely enriched his research and contributed to the effective development of his patented technologies.
Conclusion
Vassilios Kalabokis stands out as an innovative inventor whose contributions to immune checkpoint modulation hold significant promise for the advancement of immunotherapy. His patents not only showcase cutting-edge scientific developments but also establish a foundation for future research aimed at treating complex diseases.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.