The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2022

Filed:

Mar. 20, 2018
Applicants:

Bio-techne Corporation, Minneapolis, MN (US);

The Regents of the University of Colorado, Denver, CO (US);

Inventors:

Vassilios Kalabokis, Fridley, MN (US);

Charles A. Dinarello, Denver, CO (US);

Assignees:

Bio-Techne Corporation, Minneapolis, MN (US);

The Regents of the University of Colorado, Denver, CO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/54 (2006.01); A61K 38/00 (2006.01); A61P 11/06 (2006.01);
U.S. Cl.
CPC ...
C07K 14/54 (2013.01); A61P 11/06 (2018.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract

The disclosure provides interleukin 37 (IL-37) fusion proteins, methods of making IL-37 fusion proteins including constructs used to express IL-37 fusion proteins, and methods of using IL-37 fusion proteins. In some embodiments, the IL-37 fusion protein includes amino acids 46-206 of isoform B of IL-37 and a heavy chain portion of an antibody.


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