Paris, France

Valerie Schiavon

USPTO Granted Patents = 2 

Average Co-Inventor Count = 5.0

ph-index = 1


Company Filing History:


Years Active: 2021-2022

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2 patents (USPTO):Explore Patents

Title: Innovations by Valerie Schiavon in Regulatory T Cell Research

Introduction

Valerie Schiavon is a prominent inventor based in Paris, France, known for her significant contributions to the field of immunology. She has been instrumental in developing methods for generating regulatory T cells, which play a crucial role in immune response and cancer therapy. With a total of 2 patents, her work has the potential to advance therapeutic strategies in treating various diseases.

Latest Patents

Valerie Schiavon's latest patents include innovative methods for the ex vivo generation of MHCII restricted CD4Foxp3 regulatory T cells and γδ Foxp3 regulatory T cells. The first patent focuses on a method for generating and expanding MHCII restricted CD4Foxp3 regulatory T cells, demonstrating optimal conditions for inducing Foxp3 expression in naive CD3+ CD4+ TCRαβ+ MHCII restricted T cells. This invention also outlines an experimental procedure to create autologous CD8+ T cell lines that can effectively target tumor-antigen specific FOXP3 expressing T cells, thereby addressing tumor cell immune evasion.

The second patent pertains to the ex vivo generation of γδ Foxp3 regulatory T cells. This invention describes the induction of Foxp3+ expression in human induced tumor-antigen specific CD4+ TCRγδ unrestricted T cells. It also details a method for generating and expanding antigen-specific Foxp3 expressing CD3+ TCRγδ+ unrestricted T cells, which are committed to regulatory activity regardless of the stimulation conditions.

Career Highlights

Throughout her career, Valerie Schiavon has worked with esteemed organizations such as the Institut National de la Santé et de la Recherche Médicale and Médecine et Innovation. Her research has significantly impacted the understanding of T cell regulation and its therapeutic applications.

Collaborations

Valerie has collaborated with notable professionals in her field, including Daniel Zagury and Helene Le Buanec. These collaborations have further enriched her research and contributed to the advancement of immunological studies.

Conclusion

Valerie Schiavon's innovative work in the field of regulatory T cells showcases her dedication to advancing medical science. Her patents reflect a commitment to developing effective therapeutic strategies that could transform cancer treatment and immunology.

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