This inventor holds 2 USPTO granted patents and 1 published patent application. Top assignees: Merck Patent Gesellschaft, Merck Patent Gmbh. Active years: 2002-2011.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Bad Frankenhausen, DE (2002)
- Rottleben, DE (2011)
Company Filing History:
Years Active: 2002-2011
Title: Uwe Horn: Innovator in Protein Expression Technologies
Introduction
Uwe Horn is a notable inventor based in Munich, Germany. He has made significant contributions to the field of biotechnology, particularly in the area of protein expression. With a total of 2 patents, his work focuses on improving the efficiency and yield of recombinant proteins.
Latest Patents
Horn's latest patents include a method for improved protein expression in bacteria by monitoring and modulating protein folding. This invention relates to a new method for enhancing functional protein expression, whereby the folding process is monitored through online measurement. If necessary, the protein folding can be influenced by adding folding-promoting agents and/or co-expression of the periplasmic chaperone (Skp). This technology offers a way to improve the yield of functionally expressed recombinant proteins. Another significant patent is the process for the preparation of recombinant proteins in E. coli by high cell density fermentation. This invention describes a fed-batch fermentation process that utilizes special host/vector systems to efficiently produce recombinant proteins, particularly recombinant antibody molecules and miniantibodies. Under the specified conditions, the cells can grow at a maximum specific growth rate, achieving high space-time yields of recombinant proteins.
Career Highlights
Throughout his career, Uwe Horn has worked with prominent companies such as Merck Patent Gesellschaft and Merck Patent GmbH. His experience in these organizations has contributed to his expertise in the field of biotechnology and patent development.
Collaborations
Horn has collaborated with notable colleagues, including Wolfgang Strittmatter and Siegfried Matzku. These partnerships have further enriched his work and innovations in protein expression technologies.
Conclusion
Uwe Horn's contributions to the field of biotechnology, particularly in protein expression, highlight his innovative spirit and dedication to advancing scientific knowledge. His patents reflect a commitment to improving the efficiency of recombinant protein production, which has significant implications for various applications in medicine and research.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile