Ute E Burkhardt

Title: Ute E Burkhardt: Innovator in T-Cell Receptor Profiling

Introduction

Ute E Burkhardt is a notable inventor based in Belmont, MA (US). She has made significant contributions to the field of immunology, particularly in the profiling of T-cell receptors. With a total of 2 patents, her work has implications for personalized medicine and cancer therapies.

Latest Patents

Burkhardt's latest patents focus on methods for profiling the T-cell-receptor repertoire. The first patent describes techniques for profiling subject-specific and personalized T cell receptor (TCR) repertoires using a single-cell sequencing method. This method allows for the determination of binding between T cell receptors and subject-specific neoantigens. Additionally, it identifies the antigenic targets of T cell receptors in the context of tumor neoantigens. The implications of this work extend to understanding the basic mechanisms of the mammalian immune response and developing antigen-specific diagnostic markers and therapies. Furthermore, cloned TCRs can be utilized to formulate personalized immunotherapies for diseases such as cancer.

Career Highlights

Throughout her career, Ute E Burkhardt has worked with prestigious organizations, including the Broad Institute, Inc. and Dana-Farber Cancer Institute Inc. Her research has significantly advanced the understanding of T cell responses and their applications in treating various diseases.

Collaborations

Burkhardt has collaborated with esteemed colleagues, including Nir Hacohen and Catherine Ju-Ying Wu. These collaborations have further enriched her research and contributed to the advancement of immunological studies.

Conclusion

Ute E Burkhardt's innovative work in T-cell receptor profiling has the potential to revolutionize personalized medicine and cancer treatment. Her contributions to the field are invaluable and continue to inspire future research in immunology.