Ulf Hans Eskil Soderlind

Title: Ulf Hans Eskil Soderlind: Innovator in Protein Function Evolution

Introduction

Ulf Hans Eskil Soderlind is a notable inventor based in Sòdra Sandby, Sweden. He has made significant contributions to the field of molecular evolution, particularly in the development of methods for enhancing protein function. With a total of four patents to his name, Soderlind's work has implications for biotechnology and therapeutic applications.

Latest Patents

Soderlind's latest patents include a method for in vitro molecular evolution of protein function. This invention focuses on creating molecular libraries that allow for the variability and modification of protein functions through the shuffling of polynucleotide sequence segments. By incorporating variant peptide regions into defined peptide regions, proteins with desired characteristics can be obtained. This method is particularly useful for generating antibodies with specific traits by isolating individual CDR DNA sequences and integrating them into a scaffold from a different antibody.

Another significant patent involves a method for in vitro molecular evolution of protein function that utilizes an exonuclease enzyme and two populations of parent polynucleotide sequences. This innovative approach allows for the shuffling of nucleotide segments derived from exonuclease digestion, enabling the generation of polypeptides with modified characteristics compared to their parent proteins. This method has potential applications in creating new proteins, such as antibodies and enzymes.

Career Highlights

Throughout his career, Soderlind has worked with prominent companies in the biotechnology sector, including BioInvent International AB and Alligator Bioscience AB. His experience in these organizations has contributed to his expertise in protein engineering and molecular evolution.

Collaborations

Soderlind has collaborated with notable colleagues in his field, including Carl Arne Krister Borrebaeck and Rebecka Ingrid Camilla Ottosson. These collaborations have likely enriched his research and development efforts in protein function evolution.

Conclusion

Ulf Hans Eskil Soderlind is a distinguished inventor whose work in molecular evolution has paved the way for advancements in protein engineering. His innovative methods and collaborations continue to influence the biotechnology landscape.