Tyson Bowen

Title: Tyson Bowen: Innovator in Nucleic Acid Amplification

Introduction

Tyson Bowen is a notable inventor based in Union City, CA (US). He has made significant contributions to the field of molecular biology, particularly in the area of nucleic acid amplification. His innovative methods have the potential to enhance the efficiency and specificity of genetic research.

Latest Patents

Tyson Bowen holds a patent for "Methods for selectively amplifying and tagging nucleic acids." This patent describes methods for adding sequence tags during the amplification of a nucleic acid target. The target is amplified using two sets of primers that are modified so that only tagged targets can ligate to hairpin adapters, which protect them from subsequent exonuclease treatment. The patent also includes methods for creating circular nucleic acids, where specific overhangs are generated by exonuclease trimming with a polymerase. This ensures that only desired targets can ligate to sticky-ended hairpin adapters, providing further protection from exonuclease treatment. Additionally, the patent describes compositions, kits, and systems related to these methods.

Career Highlights

Tyson Bowen is currently associated with Pacific Biosciences of California, Inc., a company known for its advancements in DNA sequencing technology. His work at this organization has allowed him to contribute to cutting-edge research and development in the field.

Collaborations

Tyson collaborates with various professionals in his field, including his coworker Walter H. Lee. Their combined expertise enhances the innovative efforts at Pacific Biosciences.

Conclusion

Tyson Bowen's contributions to nucleic acid amplification represent a significant advancement in molecular biology. His patented methods and ongoing work at Pacific Biosciences continue to push the boundaries of genetic research and technology.