Tujin Shi

Title: Tujin Shi: Innovator in Biological Analysis and Prostate Cancer Research

Introduction

Tujin Shi is a notable inventor based in Richland, WA (US), recognized for his contributions to the fields of biological analysis and prostate cancer research. With a total of 2 patents, his work focuses on innovative methods for quantifying target analytes in complex biological systems and diagnosing prostate cancer.

Latest Patents

One of Tujin Shi's latest patents is a process for ultra-sensitive quantification of target analytes in complex biological systems. This invention discloses antibody-free processes that provide accurate quantification of a wide variety of low-abundance target analytes in complex samples. The processes can employ high-pressure, high-resolution chromatographic separations for analyte enrichment. Intelligent selection of target fractions may be performed via on-line Selected Reaction Monitoring (SRM) or off-line rapid screening of internal standards. Quantification may be performed on individual or multiplexed fractions. Applications include analyses of very low abundance proteins or candidate biomarkers in plasma, cell, or tissue samples without the need for affinity-specific reagents.

Another significant patent involves methods for treating and diagnosing subjects with prostate cancer. This patent outlines methods for measuring increased expression of at least two prostate cancer-related molecules in a sample obtained from a subject. The molecules include AGR2, AGR3, CRISP3, CCL3, CEACAM5, CEACAM6, IL24, MMP9, CXCL14, CD90, POSTN, and SFRP4. The methods can include administering therapy to a subject with prostate cancer, particularly for those with intermediate- or high-risk prostate cancer.

Career Highlights

Tujin Shi has worked with prominent organizations such as Battelle Memorial Institute and the University of Washington. His experience in these institutions has contributed significantly to his research and innovations in the field.

Collaborations

Throughout his career, Tujin has collaborated with notable colleagues, including Weijun Qian and Thomas L. Fillmore. These collaborations have further enhanced his research capabilities and contributions to the scientific community.

Conclusion

Tujin Shi's innovative work in biological analysis and prostate cancer research showcases his dedication to advancing medical science. His patents reflect a commitment to improving diagnostic methods and treatment options for patients.