Trevor J Trust

Title: Trevor J Trust: Innovator in Immunogenicity and Pathogen Detection

Introduction

Trevor J Trust is a notable inventor based in Sherborn, MA (US). He has made significant contributions to the field of immunogenicity and pathogen detection, holding a total of 2 patents. His work has implications for vaccine development and the detection of pathogenic strains.

Latest Patents

Trevor's latest patents include a recombinant protein that comprises the maltose binding protein (MBP) fused to amino acids 5–337 of the FlaA flagellin of VC167. This invention has provided evidence of immunogenicity and protective efficacy against challenges by a heterologous strain of 81–176 in mammals. Additionally, it includes a recombinant DNA construct encoding the immunodominant region of flagellin for use as a component of a vaccine against diarrhea. This invention represents an effective treatment while avoiding the induction of Guillain Barre Syndrome (GBS), a post-infection polyneuropathy caused by molecular mimicry of human gangliosides.

Another significant patent involves a specific set of oligonucleotide PCR primers (pg50 and pg3) and a specific oligonucleotide probe (pBA273) for the detection of PCR-amplified DNA from pathogenic strains of Campylobacter, specifically C. coli and C. jejuni, in fecal specimens.

Career Highlights

Trevor J Trust works in the USA as a representative of the Secretary of the Navy. His role involves applying his innovative research to practical applications that benefit public health and safety.

Collaborations

Trevor has collaborated with notable colleagues such as Patricia Guerry and Lanfong H Lee, contributing to advancements in his field.

Conclusion

Trevor J Trust's innovative work in immunogenicity and pathogen detection showcases his commitment to advancing medical science and public health. His patents reflect a dedication to creating effective solutions for pressing health challenges.