Location History:
- Slough Berkshire, GB (2020)
- Slough, GB (2021 - 2024)
Company Filing History:
4 out of 109 
1 out of 1,451 
Years Active: 2020-2024
Title: Tracy Lynn Arakaki: Innovator in Anti-TNFα Antibodies
Introduction
Tracy Lynn Arakaki is a prominent inventor based in Slough, GB. She has made significant contributions to the field of biotechnology, particularly in the development of anti-TNFα antibodies. With a total of 4 patents to her name, her work has the potential to impact therapeutic approaches for various diseases.
Latest Patents
One of her latest patents is focused on methods of use of anti-TNFα antibodies. This patent demonstrates that certain compounds can bind to TNF and stabilize a conformation of trimeric TNF that binds to the TNF receptor. The antibodies disclosed in this patent selectively bind to complexes of such compounds with TNF superfamily members. These antibodies may be utilized to detect further compounds with similar activity and serve as target engagement biomarkers.
Another significant patent involves a method of identifying potential inhibitors of APO TNFα trimers. This patent reveals a new, stable trimeric TNFα structure with distorted symmetry that can bind to the TNFR1 receptor, attenuating signaling. This innovation can be used in the treatment and prevention of diseases associated with the soluble TNFα/TNFR1 interaction. Importantly, membrane-bound TNFα retains its ability to signal through TNFR2, allowing for therapies that do not significantly increase the risk of infection or malignancy.
Career Highlights
Throughout her career, Tracy has worked with notable companies such as UCB Biopharma and Sanofi. Her experience in these organizations has contributed to her expertise in the field of biotechnology and patent development.
Collaborations
Tracy has collaborated with esteemed colleagues, including James Philip O'Connell and John Robert Porter. These partnerships have further enriched her research and innovation efforts.
Conclusion
Tracy Lynn Arakaki is a trailblazer in the field of anti-TNFα antibodies, with a strong portfolio of patents that showcase her innovative spirit. Her work continues to pave the way for advancements in therapeutic solutions for various diseases.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.