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For the Inventor, By the Inventor

Okayama, Japan

Toshio Kunikata

USPTO Granted Patents = 12

Average Co-Inventor Count = 5.1

ph-index = 5

Forward Citations = 76(Granted Patents)


Company Filing History:

goldMedal12 out of 375 
 
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
 patents

Years Active: 1999-2008

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12 patents (USPTO):Explore Patents
1. 7405048 - Method for detecting a polypeptide which induces interferon-γ production (2008-07-29),
2. 7355014 - Interferon-γ inducing polypeptide, pharmaceutical composition thereof, monoclonal antibody thereto, and methods of use (2008-04-08),
3. 7141393 - Interleukin-18-receptor proteins (2006-11-28),
4. 7135458 - Interferon-γ inducing polypeptide, pharmaceutical composition thereof, monoclonal antibody thereto, and methods of use (2006-11-14),
5. 6600022 - Monoclonal antibody for human IL-18 receptor (2003-07-29),
6. 6524625 - Physiologically active extract obtained from indigo plant polygonum tinctorium (2003-02-25),
7. 6509449 - Monoclonal antibody specific to polypeptide which induces interferon-G&ggr; production (2003-01-21),
8. 6277598 - DNA molecule encoding interferon-gamma (IFN-&lgr;) inducing factor (IGIF, IL-18) and DNA fragment thereof (2001-08-21),
9. 6274709 - Interferon-gamma (IFN-&ggr;) inducing factor (IGIF, IL-18) and peptide fragment thereof (2001-08-14),
10. 6268486 - Process for purifying a polypeptide (2001-07-31),
11. 6197297 - Monoclonal antibody specific to polypeptide which induces interferon-gamma production (2001-03-06),
12. 5914253 - Recombinant production of murine interferon--.gamma. (IFN-.gamma.) (1999-06-22),

Title: Innovations of Toshio Kunikata

Introduction

Toshio Kunikata is a prominent inventor based in Okayama, Japan. He has made significant contributions to the field of biotechnology, particularly in the development of polypeptides and monoclonal antibodies. With a total of 12 patents to his name, Kunikata's work has the potential to impact various medical treatments.

Latest Patents

Kunikata's latest patents include a method for detecting a polypeptide that induces interferon-γ production. This involves a monoclonal antibody specific to a polypeptide with a molecular weight of 18,500±3,000 daltons on SDS-PAGE and a pI of 4.9±1.0 on chromatofocusing. The monoclonal antibody can be obtained from hybridomas and is useful for the purification and detection of the polypeptide. This polypeptide strongly induces IFN-γ production by immunocompetent cells with minimal side effects, even at relatively high doses. Another significant patent involves a human IFN-γ inducing polypeptide, which has been isolated, purified, and characterized. Pharmaceutical compositions containing this novel polypeptide can be formulated, and monoclonal antibodies can be raised against it. This polypeptide can be utilized in treating diseases susceptible to INF-γ treatment and enhancing the cytotoxicity of NK cells.

Career Highlights

Kunikata is associated with Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, where he has been instrumental in advancing research in his field. His innovative approaches have led to breakthroughs in understanding and utilizing polypeptides for therapeutic purposes.

Collaborations

Kunikata has collaborated with notable colleagues such as Masashi Kurimoto and Mutsuko Taniguchi. Their combined expertise has contributed to the success of various research projects and patent developments.

Conclusion

Toshio Kunikata's work exemplifies the impact of innovation in biotechnology. His patents and research continue to pave the way for advancements in medical treatments, showcasing the importance of inventors in the scientific community.

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