The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 21, 2001

Filed:

Feb. 19, 1999
Applicant:
Inventors:

Haruki Okamura, Osaka, JP;

Tadao Tanimoto, Okayama, JP;

Kakuji Torigoe, Okayama, JP;

Toshio Kunikata, Okayama, JP;

Mutsuko Taniguchi, Okayama, JP;

Keizo Kohno, Okayama, JP;

Masashi Kurimoto, Okayama, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/524 ; C07K 1/454 ;
U.S. Cl.
CPC ...
C12N 1/524 ; C07K 1/454 ;
Abstract

A protein which induces the IFN-&ggr; production by immunocompetent cells and has a molecular weight of 19,000±5,000 daltons on SDS-PAGE or gel filtration method and a pI of 4.8±1.0 on chromatofocusing. The protein is isolated from mouse liver and can be purified by a monoclonal antibody specific to it. The monoclonal antibody can be also used for assaying the protein. Fragments of the protein can be used for production of antibodies, and can be produced recombinantly using appropriate medric acids, host cells and vectors. Fragments of nuclear acids may also be used as probes.


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