The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 2008

Filed:

Oct. 16, 2006
Applicants:

Shimpei Ushio, Okayama, JP;

Kakuji Torigoe, Okayama, JP;

Todao Tanimoto, Okayama, JP;

Haruki Okamura, Osaka, JP;

Masashi Kurimoto, Okayama, JP;

Shigeharu Fukuda, Okayama, JP;

Toshio Kunikata, Okayama, JP;

Mutsuko Taniguchi, Okayama, JP;

Keizo Kohno, Okayama, JP;

Inventors:

Shimpei Ushio, Okayama, JP;

Kakuji Torigoe, Okayama, JP;

Todao Tanimoto, Okayama, JP;

Haruki Okamura, Osaka, JP;

Masashi Kurimoto, Okayama, JP;

Shigeharu Fukuda, Okayama, JP;

Toshio Kunikata, Okayama, JP;

Mutsuko Taniguchi, Okayama, JP;

Keizo Kohno, Okayama, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/18 (2006.01); C07K 16/24 (2006.01); C12P 21/08 (2006.01); A61K 38/00 (2006.01); A61K 38/19 (2006.01); C07K 14/00 (2006.01); C07K 14/54 (2006.01);
U.S. Cl.
CPC ...
Abstract

A human IFN-γ inducing polypeptide and its nucleotide sequence was isolated, purified and characterized. Pharmaceutical compositions containing this novel INF-γ inducing polypeptide or active fragments thereof are formulated and monoclonal antibodies are raised against this polypeptide or antigenic fragments thereof. The polypeptide can be used in a method for treating diseases susceptive to treatment with INF-γ, and methods for enhancing the cytotoxicity of NK cells or for inducing the formation of LAK cells, such as to treat tumors and malignant pathologies.


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