Location History:
- Ibaragi, JP (1993 - 1994)
- Ibaraki, JP (1992 - 1996)
- Osaki-Shi, Osaka-Fu JP (1998)
- Osaka-Shi, Osaka-Fu JP (2001)
- Osaka-shi, Osaka JP (2002)
- Suminoe-Ku, Osaka-shi, Osaka-Fu JP (2001 - 2003)
- Osaka-shi, JP (1999 - 2006)
- Osaka-shi, Osaka-fu, JP (2007)
Company Filing History:
5 out of 1,929 
4 out of 9 
1 out of 281 
Years Active: 1992-2007
Title: Innovations by Toshio Hirano: Pioneering Advances in Cytokine Research
Introduction
Toshio Hirano, an esteemed inventor based in Osakashi, Japan, has significantly contributed to the field of biomedicine with a total of 15 patents to his name. His groundbreaking research focuses on the mechanisms of cytokine signaling and the development of therapeutic methods for treating associated diseases.
Latest Patents
Among his latest innovations is a patent for a method of screening for substances that prevent or treat diseases linked to the malfunction of the IL-6 family cytokine receptor. This invention employs a transgenic mouse model that expresses a specific variant of the gp130 protein, which includes modifications to a particular tyrosine residue. This method offers novel pathways for identifying potential therapies.
Another notable patent involves a gene that encodes a novel membrane protein with pre-B cell growth-supporting capabilities. This invention details a technique for producing the membrane protein and generating monoclonal antibodies to assist in the clinical diagnosis of rheumatoid arthritis. The discovery is pivotal for understanding and addressing autoimmune conditions through the development of targeted therapies.
Career Highlights
Throughout his career, Toshio Hirano has collaborated with prominent organizations, including Ajinomoto Co., Ltd. His research has not only propelled advancements in therapeutic strategies but has also positioned him as a leading figure in cytokine-related studies.
Collaborations
Hirano’s contributions have been bolstered through collaborations with renowned colleagues such as Tadamitsu Kishimoto and Tsuneyasu Kaisho. These partnerships have led to significant strides in understanding cytokine signaling and its implications in diseases, fostering an environment of innovative research within the scientific community.
Conclusion
Toshio Hirano stands out as a key inventor whose work has the potential to transform therapeutic approaches to inflammatory diseases. With a focus on cytokine signaling and innovative methodologies, his patents reflect a deep commitment to advancing medical science and improving patient outcomes. His contributions continue to inspire future research in the field.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.