The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 01, 1993
Filed:
Oct. 22, 1990
Applicant:
Inventors:
Tadamitsu Kishimoto, Tondabayashi, JP;
Toshio Hirano, Ibaragi, JP;
Shizuo Akira, Minoo, JP;
Hiroshi Isshiki, Osaka, JP;
Osamu Tanabe, Hiroshima, JP;
Shigemi Kinoshita, Ibaragi, JP;
Takuya Shimamoto, Minoo, JP;
Assignee:
Tadamitsu Kishimoto, Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ; C12N / ; C12N / ; C12N / ; C12N / ; C12N / ; A61K / ; C07H / ;
U.S. Cl.
CPC ...
435 691 ; 435 91 ; 4351723 ; 4352523 ; 43525233 ; 4352401 ; 435255 ; 435256 ; 4353201 ; 536 235 ; 530300 ; 735-6 ; 735 29 ; 735 41 ; 735 56 ; 735 61 ; 735 73 ;
Abstract
This invention relates to a gene which codes for the IL-6 gene expression inducing nuclear factor C/EBP2 capable of binding sequence-specifically to the palindrome structure SEQ ID NO:2 located in the transcriptional regulatory region of the IL-6 gene; an expression plasmid with the C/EBP2 gene incorporated therein; an transformant harboring the expression plasmid; a recombinant C/EBP2 obtained by expressing the C/EBP2 gene; and a method of producing the recombinant C/EBP2.