This inventor holds 2 USPTO granted patents. Top assignee: Japan Science and Technology Agency. Active years: 2006.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2006
Title: Innovations by Toshihiro Nukiwa
Introduction
Toshihiro Nukiwa is a prominent inventor based in Sendai, Japan. He has made significant contributions to the field of medical research, particularly in developing animal models for studying diseases. With a total of 2 patents, his work has the potential to advance therapeutic approaches for serious health conditions.
Latest Patents
Nukiwa's latest patents include a model for Goodpasture's syndrome and a model for rheumatoid arthritis. The Goodpasture's syndrome model mouse is designed to aid in the treatment of this condition, which has historically lacked adequate disease models. This invention allows for the screening of remedies and early diagnosis of Goodpasture's syndrome. The model is created by immunizing an immunoglobulin Fcγ receptor IIB knockout mouse with type IV collagen, which induces the syndrome.
Additionally, Nukiwa has developed a model animal for rheumatoid arthritis, where the severity of the condition reaches its maximum level with a 100% onset ratio. This model is constructed by backcrossing a deficient immunoglobulin Fcγ receptor IIB gene mouse with a wild-type collagen-induced arthritis-susceptible DBA/1J mouse. The model mouse is then immunized with bovine joint-origin type II collagen to develop collagen-induced arthritis, facilitating the screening of potential remedies.
Career Highlights
Toshihiro Nukiwa is affiliated with the Japan Science and Technology Agency, where he continues to contribute to innovative research. His work is crucial in bridging the gap between basic research and clinical applications, particularly in the realm of autoimmune diseases.
Collaborations
Nukiwa collaborates with notable colleagues, including Toshiyuki Takai and Akira Nakamura. Their combined expertise enhances the research efforts and fosters a collaborative environment for innovation.
Conclusion
Toshihiro Nukiwa's contributions to medical research through his innovative patents are paving the way for advancements in the treatment of complex diseases. His work exemplifies the importance of developing effective models for understanding and addressing health challenges.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile