The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7081562 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 25, 2006

Filed:

Jul. 26, 2000
Applicants:

Akira Nakamura, Sendai, JP;

Toshihiro Nukiwa, Sendai, JP;

Toshiyuki Takai, Sendai, JP;

Inventors:

Akira Nakamura, Sendai, JP;

Toshihiro Nukiwa, Sendai, JP;

Toshiyuki Takai, Sendai, JP;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a model animal with favorite onset of rheumatoid arthritis wherein the severity of arthritis reaches the maximum level and its onset ratio is a hundred percent, and a screening method of a remedy for rheumatoid arthritis by using the model animal. A mouse whose function of immunoglobulin Fcγ receptor IIB gene is deficient on its chromosome and a wild-type collagen-induced arthritis-susceptible DBA/1J mouse are backcrossed six times or more, and a model mouse with favorite onset of rheumatoid arthritis is constructed. This model mouse with favorite onset of rheumatoid arthritis is immunized with bovine joint-origin type II collagen to develop collagen-induced arthritis.


Find Patent Forward Citations

Nakamura, Akira. (2006). Model animal with favorite onset or rheumatoid arthritis (U.S. Patent No. 7081562). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7081562

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