Toshihiro Komeda

Title: The Innovations of Toshihiro Komeda

Introduction

Toshihiro Komeda is a notable inventor based in Kanagawa, Japan. He has made significant contributions to the field of biotechnology, particularly in the production of glycoproteins. With a total of 4 patents to his name, his work has had a considerable impact on the industry.

Latest Patents

One of his latest patents is focused on a process for producing a glycoprotein that comprises a mammalian type sugar chain. This invention involves introducing an α-1,2-mannosidase gene into a methylotrophic yeast that has a mutation of a sugar chain biosynthesizing enzyme gene. The process allows for the production of a neutral sugar chain identical to the high mannose type sugar chain produced by mammalian cells, such as human cells. This innovation enables the large-scale production of glycoproteins with high purity. Another significant patent involves the Candida boidini dihydroxyacetone synthase promoter. This invention relates to a promoter for the dihydroxyacetone synthase gene, along with an expression cassette or vector that includes the promoter and a heterologous gene. The method allows for the efficient production of expression products from the heterologous gene.

Career Highlights

Throughout his career, Toshihiro Komeda has worked with prominent organizations such as Kirin Beer and the National Institute of Advanced Industrial Science and Technology. His experience in these institutions has contributed to his expertise in biotechnology and innovation.

Collaborations

Toshihiro has collaborated with notable colleagues, including Nobuo Kato and Yasuyoshi Sakai. These partnerships have further enhanced his research and development efforts in the field.

Conclusion

Toshihiro Komeda's contributions to biotechnology through his innovative patents and collaborations highlight his role as a significant inventor in the industry. His work continues to influence the production of glycoproteins and advancements in related technologies.