The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2001
Filed:
Apr. 28, 1999
Toshihiro Komeda, Kanagawa, JP;
Kirin Beer Kabushiki Kaisha, Tokyo, JP;
Abstract
The present invention relates to a DNA comprising the nucleotide sequence shown in SEQ ID NO:1, or a DNA for enhancing promoter activity which comprises a nucleotide sequence having deletions, substitutions, additions or insertions of one or more nucleotides in the nucleotide sequence shown in SEQ ID NO:1; to a mutant promoter comprising one or more fragments of the DNA; to a recombinant expression vector comprising the mutant promoter together with a heterologous gene; to a transformant prepared by transforming a host cell with the vector; to a process for preparing an expression product, comprising culturing the transformant in a medium, and recovering the expression product of a heterologous gene from the obtained culture; and to a method for enhancing a promoter activity, characterized in that one or more fragments of the above-defined DNA are located at at least one position preceding, following or within a selective promoter in a forward or reverse direction.