Company Filing History:
Years Active: 2018-2024
Title: The Innovations of Tomoko Shimizu: Advancements in Sulfation Enzymes
Introduction
Tomoko Shimizu is a distinguished inventor based in Kanagawa, Japan, renowned for her contributions to biochemical innovations. With a remarkable portfolio of 5 patents, she has made significant strides in the field of enzyme research, particularly focusing on 2-O-sulfation and 3-O-sulfation enzyme mutants.
Latest Patents
Among her latest patents are innovative discoveries related to the 2-O-sulfation enzyme mutant and the 3-O-sulfation enzyme mutant, detailing methods for utilizing these high-activity enzymes. The primary focus of her inventions revolves around a mutant of the 2-O-sulfation enzyme that includes a critical substitution of a leucine residue at position 321 with a basic amino acid residue. This advancement is built upon various amino acid sequences, enhancing the enzyme's transfer activity. Her work not only highlights the utility of these mutants in biotechnology but also opens new pathways for further research and application.
Career Highlights
Tomoko Shimizu has built her impressive career at Ajinomoto Co., Ltd., a leader in food and biotechnology solutions. Her work has greatly contributed to the understanding and manipulation of sulfation enzymes, making her inventions pivotal in various scientific applications.
Collaborations
Shimizu collaborates with esteemed colleagues, including Shunsuke Yamazaki and Kenichi Mori, fostering a dynamic research environment that promotes innovation. These collaborations have been instrumental in advancing her projects and achieving groundbreaking results in enzyme modifications.
Conclusion
Tomoko Shimizu stands out as an influential inventor whose work on sulfation enzymes has the potential to impact numerous fields, from pharmaceuticals to biotechnology. Her patents reflect a commitment to advancing scientific knowledge and a passion for innovation, ensuring her place in the legacy of great inventors.
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