This inventor holds 5 USPTO granted patents and 5 published patent applications, plus 1 CIPO patent and 1 EPO patent. Top assignees: Fuso Pharmaceutical Industries, Ltd., Hokkaido University. Active years: 2020-2023.
Company Filing History:
5 out of 108 
5 out of 442 
Years Active: 2020-2023
Title: Tomohiro Okagawa: Innovator in Genetic Engineering
Introduction
Tomohiro Okagawa is a prominent inventor based in Hokkaido, Japan. He has made significant contributions to the field of genetic engineering, particularly in the development of expression vectors and antibodies. With a total of 5 patents, his work has the potential to impact various medical applications.
Latest Patents
Okagawa's latest patents include innovative technologies that enhance protein production in mammalian cells. One notable invention is a vector that includes a translation-impaired dihydrofolate reductase gene cassette. This invention allows mammalian host cells to produce high levels of foreign gene-derived proteins. The introduction of a ubiquitously acting chromatin opening element (UCOE) into the expression vector enables the selection of strains that thrive in hypoxanthine-thymidine-free medium, leading to increased protein production.
Another significant patent is the development of an anti-PD-L1 antibody for detecting PD-L1 in tumor cells, such as melanoma cells. This antibody comprises specific amino acid sequences that enhance its effectiveness in staining tumor cells. Additionally, Okagawa has provided a method for preparing this antibody, which could be crucial for cancer diagnostics.
Career Highlights
Throughout his career, Okagawa has worked with esteemed institutions, including Hokkaido University and Fuso Pharmaceutical Industries, Ltd. His experience in these organizations has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Okagawa has collaborated with notable colleagues, including Satoru Konnai and Kazuhiko Ohashi. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.
Conclusion
Tomohiro Okagawa is a distinguished inventor whose work in genetic engineering has led to significant advancements in the field. His patents reflect a commitment to improving medical technologies and enhancing our understanding of genetic expression. His contributions will undoubtedly continue to influence future research and development in biotechnology.