Company Filing History:
3 out of 43 
2 out of 5 Years Active: 2018
Title: Tirtsa Kleinman: Innovator in Therapeutic Oligonucleotides
Introduction
Tirtsa Kleinman is a prominent inventor based in Jerusalem, Israel. She has made significant contributions to the field of therapeutic oligonucleotides, holding three patents that showcase her innovative work. Her research focuses on enhancing the efficacy and specificity of nucleic acid molecules for therapeutic applications.
Latest Patents
Kleinman's latest patents include groundbreaking inventions such as "Therapeutic oligonucleotides comprising pyrazolotriazine nucleotide analogues." This patent discloses double-stranded RNA nucleic acid molecules that incorporate at least one pyrazolotriazine nucleotide analog. These molecules are modified to exhibit increased on-target activity, enhanced target specificity, improved nuclease stability, reduced off-target activity, and decreased immunogenicity compared to unmodified or similarly modified dsRNA. Another notable patent is "Pyrazolotriazolyl nucleoside analogues and oligonucleotides comprising them," which relates to pyrazolotriazolyl nucleoside analogs.
Career Highlights
Throughout her career, Kleinman has worked with various companies, including Bio-Lab, Inc. and Qbi Enterprises Ltd. Her work in these organizations has contributed to advancements in the field of biotechnology and therapeutic development.
Collaborations
Kleinman has collaborated with notable professionals in her field, including Jean-Christophe Truffert and Jean Hildesheim. These collaborations have further enriched her research and innovation efforts.
Conclusion
Tirtsa Kleinman is a distinguished inventor whose work in therapeutic oligonucleotides has the potential to revolutionize treatment methodologies. Her patents reflect her commitment to advancing medical science and improving patient outcomes.