Durham, NC, United States of America

Timothy Mark Willson

USPTO Granted Patents = 20 

Average Co-Inventor Count = 2.7

ph-index = 12

Forward Citations = 420(Granted Patents)


Company Filing History:


Years Active: 1997-2012

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20 patents (USPTO):

Title: The Innovative Contributions of Timothy Mark Willson

Introduction

Timothy Mark Willson, based in Durham, NC, is a notable inventor recognized for his significant contributions to the field of biochemistry and pharmacology. With a total of 20 patents to his name, he has made an impressive mark in the world of innovation, particularly in relation to orphan nuclear receptors and their applications in drug development.

Latest Patents

Among his most recent patents, Willson has developed a novel orphan nuclear receptor that interacts with the cytochrome P-450 monooxygenase (CYP) promoter. This invention involves a receptor activated by compounds that induce CYP gene expression, along with methods for creating the receptor and utilizing nucleic acid sequences encoding it. Additionally, he has patented methods that involve non-human animals transformed to express the human receptor, enabling the screening of compounds for potential drug interactions and toxicities.

Another significant patent is centered around purine derivatives functioning as liver X receptor agonists. This invention includes methods for preventing or treating LXR-mediated diseases such as cardiovascular disease and atherosclerosis. The patented compounds and their pharmaceutical compositions offer promising avenues for medical research and treatment.

Career Highlights

Timothy Mark Willson has worked with distinguished companies throughout his career, including Glaxo Wellcome Inc. and SmithKline Beecham Corporation. His extensive experience in these organizations has allowed him to contribute to groundbreaking research and innovation in the pharmaceutical industry.

Collaborations

Throughout his career, Willson has collaborated with esteemed colleagues. Notable collaborators include Steven Anthony Kliewer and Jon Loren Collins, both of whom have played significant roles in advancing research initiatives that complement Willson's innovative projects.

Conclusion

Timothy Mark Willson's contributions to the field of innovation and invention are remarkable, particularly in the development of biological compounds that hold potential for treating serious health conditions. His patents reflect a deep commitment to advancing scientific understanding and improving human health through innovative research and collaboration with his peers.

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