Location History:
- Silver Spring, MD (US) (2009 - 2010)
- Washington, DC (US) (2012 - 2013)
Company Filing History:
2 out of 893 
2 out of 2 
2 out of 14 
Years Active: 2009-2013
Title: Innovator Timothy J. O'Leary - Advancing Histological Techniques
Introduction
Timothy J. O'Leary, hailing from Washington, DC, is a notable inventor with a rich background in enhancing biomolecular analysis. With a total of four patents to his name, O'Leary has significantly contributed to the field of histology and molecular recovery.
Latest Patents
Among his latest inventions, O'Leary has developed methods for pressure-assisted molecular recovery (PAMR) of biomolecules, pressure-assisted antigen retrieval (PAAR), and pressure-assisted tissue histology (PATH). These innovative techniques provide a method for reversing fixation-induced cross-linking in tissue specimens, which have long been preserved for histological examination. The process involves placing fixed tissue in a liquid under elevated temperature and pressure, enabling the restoration of antigenicity to proteins and enhancing molecular and proteomic analysis. Furthermore, these methods improve tissue processing for histological examination by utilizing elevated pressure conditions that enhance the perfusion of liquid reagents and reduce processing times.
Career Highlights
Throughout his career, Timothy J. O'Leary has been associated with several prestigious organizations, including the United States Government represented by the Department of Veterans Affairs and the United States of America as represented by the Secretary of Defense on behalf of the Armed Forces Institute of Pathology. His contributions have been integral in advancing medical technologies related to tissue examination and analysis.
Collaborations
O'Leary has collaborated with esteemed colleagues such as Jeffrey T. Mason and Carol B. Fowler. Together, they have worked on innovative research projects that address critical challenges in histological practices.
Conclusion
Timothy J. O'Leary stands out as an accomplished inventor whose work in histological methods has a profound impact on research and medical applications. His innovative techniques are paving the way for more efficient and accurate biomolecular analysis, thereby enhancing our understanding of preserved tissue specimens. Through his patents and collaborations, O'Leary continues to contribute valuable advancements to the field of histology.