Company Filing History:
Years Active: 2001-2006
Title: Innovations in Radiopharmaceuticals: The Contributions of Timothy J. Hoffman
Introduction
Timothy J. Hoffman, an accomplished inventor based in Columbia, MO, has made significant strides in the field of radiopharmaceuticals. With a portfolio of five patents, his work focuses on compounds that have the potential to improve the diagnosis and treatment of neoplastic diseases through innovative peptide conjugates.
Latest Patents
Hoffman's latest patents include groundbreaking approaches to develop gastrin receptor-avid peptide conjugates. One notable patent describes a compound designed for use as a therapeutic or diagnostic radiopharmaceutical. This compound facilitates the complexation of medically useful metals with a moiety that binds to the gastrin-releasing peptide receptor. Hoffman's method for treating subjects with neoplastic diseases involves administering an effective amount of a radiopharmaceutical containing a metal chelated with a specific chelating group. This unique approach enables the compound to target tumor cells expressing the gastrin-releasing peptide receptor and promotes subsequent internalization within the cells. Additionally, he has developed a method of forming therapeutic or diagnostic compounds by reacting metal synthons with chelating groups that are covalently linked to binding moieties.
Career Highlights
Timothy J. Hoffman is affiliated with The Curators of the University of Missouri, an esteemed institution that fosters academic excellence and research advancements. His contributions to radiopharmaceutical research place him at the forefront of innovation within this niche. His work not only reflects his dedication to advancing medical therapies but also showcases his expertise in chemical synthesis and receptor targeting.
Collaborations
Hoffman collaborates with notable colleagues in his field, including Wynn A. Volkert and Gary Sieckman. Their combined expertise enhances the potential for innovative developments in radiopharmaceutical applications, further driving research efforts at the University of Missouri and beyond.
Conclusion
Timothy J. Hoffman is not only a prolific inventor but also a key contributor to the advancements in therapeutic and diagnostic applications within the realm of radiopharmaceuticals. His work demonstrates a profound commitment to improving patient outcomes through innovative research, and his patents stand as a testament to his ingenuity and determination in this vital field. As the medical landscape evolves, Hoffman's inventions will likely play a significant role in shaping future therapies for patients with neoplastic diseases.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.