The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2006

Filed:

May. 02, 2001
Applicants:

Timothy J. Hoffman, Columbia, MO (US);

Wynn A. Volkert, Columbia, MO (US);

Gary Sieckman, Ashland, MO (US);

Charles J. Smith, Columbia, MO (US);

Hariprasad Gali, Columbia, MO (US);

Inventors:

Timothy J. Hoffman, Columbia, MO (US);

Wynn A. Volkert, Columbia, MO (US);

Gary Sieckman, Ashland, MO (US);

Charles J. Smith, Columbia, MO (US);

Hariprasad Gali, Columbia, MO (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a-moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor.


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