Tien-Yi Lee

Title: Tien-Yi Lee: Innovator in Anti-Cocaine Therapeutics

Introduction

Tien-Yi Lee is a notable inventor based in Ann Arbor, MI (US). He has made significant contributions to the field of anti-cocaine therapeutics, holding 2 patents that focus on innovative treatments for cocaine-induced conditions. His work is characterized by a commitment to developing effective solutions to combat the harmful effects of cocaine.

Latest Patents

One of Tien-Yi Lee's latest patents involves anti-cocaine compositions and treatment. The embodiments of this invention relate to highly efficient, thermostable, and long-lasting cocaine esterase (CocE) mutants. These mutants are designed to protect against the toxic and reinforcing effects of cocaine in subjects. The patent provides mutant CocE polypeptides that display thermostable esterase activity. Additionally, it outlines methods for treating cocaine-induced conditions in subjects through the administration of mutant CocE, as well as methods for high-throughput screening of candidate esterase polypeptides.

Career Highlights

Throughout his career, Tien-Yi Lee has worked with prestigious institutions such as Columbia University and the University of Michigan. His experience in these research environments has allowed him to collaborate with leading experts in the field and contribute to groundbreaking innovations.

Collaborations

Some of Tien-Yi Lee's notable coworkers include Donald W. Landry and Joanne MacDonald. Their collaborative efforts have further advanced the research and development of anti-cocaine therapeutics.

Conclusion

In summary, Tien-Yi Lee is a distinguished inventor whose work in anti-cocaine therapeutics has the potential to make a significant impact on public health. His innovative approaches and collaborations with esteemed institutions highlight his dedication to addressing critical issues related to substance abuse.