Tianchun Liu

Title: Innovations of Tianchun Liu

Introduction

Tianchun Liu is a notable inventor based in Hangzhou, China. He has made significant contributions to the field of biotechnology, particularly in the development of nitrilase enzymes. With a total of three patents to his name, Liu's work has implications for environmentally friendly industrial processes.

Latest Patents

One of Liu's latest patents involves a nitrilase derived from Arabis alpina, along with its encoding gene, vector, recombinant bacterial strain, and various applications. This invention provides a method for the manufacturing of (S)-3-cyano-5-methylhexanoic acid. The wet resting cells containing nitrilase Aa-Nit can kinetically resolve racemic IBSN at a concentration of 1.2 M, achieving a 42% conversion rate in 15 hours with an enantiomeric excess value exceeding 99%. This method is characterized as regio- and stereoselective, offering an atom-economical, mild, and environmentally friendly approach to industrial production.

Career Highlights

Liu has worked with prominent organizations such as Zhejiang Chiral Medicine Chemicals Co. Ltd. and Zhejiang University. His experience in these institutions has allowed him to advance his research and contribute to the field of chiral chemistry.

Collaborations

Throughout his career, Liu has collaborated with notable colleagues, including Youming Huang and Weirong Fan. These partnerships have facilitated the exchange of ideas and fostered innovation in their respective fields.

Conclusion

Tianchun Liu's contributions to biotechnology and his innovative patents highlight his role as a significant inventor in the industry. His work not only advances scientific knowledge but also promotes sustainable practices in manufacturing.