Company Filing History:
Years Active: 2012
Title: Innovations of Thomas Thurnherr in DNA Melting Temperature Determination
Introduction
Thomas Thurnherr is an accomplished inventor based in Lucerne, Switzerland. He has made significant contributions to the field of molecular biology, particularly in the determination of melting temperatures for DNA. His innovative approach utilizes a PCR analogy to enhance the accuracy of gene quantification.
Latest Patents
Thurnherr holds a patent titled "Determination of single peak melting temperature by PCR analogy and double sigmoid equation." This patent outlines systems and methods for determining melting temperatures, Tm, for DNA from melt curve data. The methodology allows for quantitative determination of gene amount based on peak height. By transforming the melting curve using a horizontal flip and translation, a double sigmoid equation is fitted to the data. The resulting equation-based solution is then used to determine the first derivative, such as the Tm value and peak height.
Career Highlights
Thomas Thurnherr is currently employed at Roche Molecular Systems, Inc., where he continues to advance research in molecular diagnostics. His work has been instrumental in improving the precision of DNA analysis, which is crucial for various applications in genetics and biotechnology.
Collaborations
Thurnherr collaborates with Ronald T Kurnik, contributing to the development of innovative solutions in the field of molecular biology.
Conclusion
Thomas Thurnherr's contributions to the determination of DNA melting temperatures exemplify the intersection of innovation and practical application in molecular biology. His work continues to influence the field and enhance the accuracy of genetic analysis.