Company Filing History:
Years Active: 1998-2001
Title: Thomas Seehaus: Innovator in Human Antibody Libraries
Introduction
Thomas Seehaus is a notable inventor based in Heppenheim, Germany. He has made significant contributions to the field of biotechnology, particularly in the development of human antibody libraries. With a total of 2 patents, his work has paved the way for advancements in antibody research and applications.
Latest Patents
Thomas Seehaus holds two recent patents that focus on the preparation and use of gene banks of human antibodies. The first patent, titled "Preparation and use of gene banks of human antibodies," describes a method for creating a comprehensive human-antibody library. This process involves translating mRNA from human B-lymphocytes into cDNA, followed by amplification using polymerase chain reaction (PCR). The resulting library allows for the screening of selected antigens in vitro.
The second patent, "Preparation and use of gene banks of synthetic human antibodies," outlines a technique for generating synthetic human antibodies or parts of antibodies containing the antigen-binding domain. This method utilizes a huAb framework in a suitable vector, where hypervariable regions are formed by combining oligonucleotides. The expression of this synthetic huAb cDNA in microbial systems, such as E. coli, results in a synthetic huAb library that is also available for in vitro screening.
Career Highlights
Throughout his career, Thomas Seehaus has worked with prominent companies in the biotechnology sector. Notable among these are Behring Diagnostics GmbH and Dade Behring Marburg GmbH. His experience in these organizations has contributed to his expertise in antibody research and development.
Collaborations
Thomas has collaborated with several professionals in his field, including Melvyn Little and Frank Berthold Breitling. These collaborations have further enhanced his research and innovation capabilities.
Conclusion
Thomas Seehaus is a distinguished inventor whose work in human antibody libraries has made a significant impact in biotechnology. His patents reflect his commitment to advancing the field and improving the methods for antibody research.