Company Filing History:
Years Active: 2001-2004
Title: Thomas Schäfer: Innovator in Gene Library Generation and Enzyme Variants
Introduction
Thomas Schäfer is a notable inventor based in Farum, Denmark. He has made significant contributions to the field of biotechnology, particularly in the development of methods for generating gene libraries and enzyme variants. With a total of 3 patents, his work has had a substantial impact on the industry.
Latest Patents
One of Thomas Schäfer's latest patents is a method for generating a gene library. This invention relates to a method of generating a gene library from an environmental pool of organisms, which is enriched in DNA encoding a polypeptide with an activity of interest. The invention also provides a method of selecting a DNA sequence of interest from this environmental pool. Furthermore, it relates to a gene library prepared from an enriched environmental pool of organisms that is enriched in DNA encoding a polypeptide with an activity of interest.
Another significant patent involves amylolytic enzyme variants. In this work, the inventors discovered striking, and previously unpredicted, structural similarities and differences between the structure of Novamyl and the reported structures of CGTases. Based on these findings, they constructed variants of maltogenic alpha-amylase having CGTase activity and variants of CGTase having maltogenic alpha-amylase activity. Additionally, they created hybrid enzymes with one or more improvements to specific properties of the parent enzymes using recombinant DNA methodology.
Career Highlights
Thomas Schäfer is associated with Novozymes A/S, a leading company in the field of biotechnology. His work at Novozymes has allowed him to explore innovative solutions and contribute to advancements in enzyme technology.
Collaborations
Throughout his career, Thomas has collaborated with notable colleagues, including Joel R. Cherry and Allan Svendsen. These collaborations have further enriched his research and development efforts.
Conclusion
In summary, Thomas Schäfer is a distinguished inventor whose work in gene library generation and enzyme variants has made a significant impact in biotechnology. His contributions continue to influence the field and inspire future innovations.