Wyncote, PA, United States of America

Thomas R Berka


Average Co-Inventor Count = 3.6

ph-index = 2

Forward Citations = 9(Granted Patents)


Company Filing History:


Years Active: 1993-1996

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3 patents (USPTO):Explore Patents

Title: Inventor Thomas R. Berka: A Pioneer in Protein Protease Inhibitors

Introduction

Thomas R. Berka is a distinguished inventor based in Wyncote, Pennsylvania. With a total of three patents to his name, Berka's work primarily focuses on the field of biotechnology, particularly in the development of protein protease inhibitors derived from Streptomyces. His innovative contributions have significant implications for various applications in medicine and agriculture.

Latest Patents

One of Berka's notable patents is related to a process for producing a heterologous polypeptide in Streptomyces. This invention involves transforming a Streptomyces organism with a recombinant DNA molecule that includes an LEP-10 of Ltl sequence. This sequence is fundamental as it encodes a gene expression unit, promoter sequence, or export control encoding sequence, each linked to a heterologous coding sequence. The transformed Streptomyces is then cultured to express the heterologous polypeptide.

Another significant patent revolves around novel protein protease inhibitors derived from Streptomyces, as well as the DNAs encoding these inhibitors. This invention also discusses vectors and transformed host cells useful for the recombinant production of the inhibitors, highlighting Berka's contributions to advancing biotechnology.

Career Highlights

Throughout his career, Thomas R. Berka has worked with significant organizations, including the United States of America as represented by the Secretary of and SmithKline Beecham Corporation. His work in these institutions has aided in the progress of research and development within his area of expertise, particularly in the pharmaceutical and biotechnology sectors.

Collaborations

In the course of his career, Berka has collaborated with several notable individuals, including James A. Fornwald and Joselina G. Gorniak. These collaborations reflect the collaborative nature of scientific innovation and the importance of teamwork in achieving significant breakthroughs in technology.

Conclusion

Thomas R. Berka stands out as an influential figure in the realm of inventors, particularly in the development of protein protease inhibitors from Streptomyces. His patents not only signify his innovative spirit but also contribute to advancements in biotechnology that may benefit various industries. As he continues his work, his contributions will likely have a lasting impact on future research and applications in the field.

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