The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 1996

Filed:

Dec. 03, 1993
Applicant:
Inventors:

Thomas R Berka, Wyncote, PA (US);

James A Fornwald, Norristown, PA (US);

Joselina G Gorniak, Willow Grove, PA (US);

Martin Rosenberg, Royersford, PA (US);

James E Strickler, Havertown, PA (US);

Dean P Taylor, King of Prussia, PA (US);

Assignee:

SmithKline Beckman Corporation, Philadelphia, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ;
U.S. Cl.
CPC ...
435 691 ; 435 692 ; 435 697 ; 435 698 ;
Abstract

This invention relates to a process for producing a heterologous polypeptide in Streptomyces which involves transforming a Streptomyces organism with a recombinant DNA molecule comprising an LEP-10 of LTl sequence selected from the group consisting of a sequence encoding a gene expression unit, a promoter sequence or an export control encoding sequence each operatively linked to a heterologous coding sequence and then culturing the transformed Streptomyces such that the heterologous polypeptide is expressed.


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