This inventor holds 7 USPTO granted patents and 9 published patent applications and 1 EPO patent. Top assignee: The University of North Carolina at Chapel Hill. Active years: 2006-2026.
Company Filing History:
Years Active: 2006-2026
Title: Innovations of Thomas McCown
Introduction
Thomas McCown is a notable inventor based in Carrboro, NC (US). He has made significant contributions to the field of gene therapy, particularly through his work with adeno-associated virus (AAV) vectors. With a total of 7 patents to his name, McCown's inventions are paving the way for advancements in treating neurological disorders.
Latest Patents
One of McCown's latest patents is focused on AAV vectors targeted to oligodendrocytes. This invention relates to chimeric AAV capsids that are specifically designed to target oligodendrocytes. It includes methods for delivering nucleic acids of interest to oligodendrocytes both in vitro and in vivo. Additionally, it addresses methods for delivering nucleic acids to areas of the central nervous system (CNS) that are adjacent to a compromised blood-brain barrier. This invention also outlines methods for treating disorders associated with oligodendrocyte dysfunction using the AAV capsids and virus vectors.
Another significant patent by McCown involves AAV vectors targeted to the central nervous system. This invention also features chimeric AAV capsids aimed at the CNS and includes virus vectors that utilize these capsids. The methods described in this patent focus on effectively targeting the central nervous system and oligodendrocytes.
Career Highlights
Thomas McCown is affiliated with the University of North Carolina at Chapel Hill, where he continues to innovate and contribute to research in gene therapy. His work has garnered attention for its potential to address critical health issues related to the nervous system.
Collaborations
Some of McCown's notable coworkers include Steven Gray and Rebecca P Haberman. Their collaborative efforts enhance the research and development of innovative solutions in the field.
Conclusion
Thomas McCown's contributions to the field of gene therapy through his patents and research at the University of North Carolina at Chapel Hill highlight his role as a leading inventor. His work is instrumental in advancing treatments for neurological disorders, showcasing the impact of innovation in medicine.