Company Filing History:
Years Active: 2013-2017
Title: Innovations by Thomas Mathers in Vaccine Development
Introduction
Thomas Mathers is an accomplished inventor based in Boston, MA, known for his significant contributions to the field of vaccine development. He holds two patents that focus on innovative methods for designing and preparing vaccines. His work is particularly relevant in the context of infectious agents that evade the immune system.
Latest Patents
Mathers' latest patents include "Methods for designing and preparing vaccines comprising directed sequence polymer compositions via the directed expansion of epitopes." This invention outlines a process for preparing a composition that includes directed sequence polymer (DSP) mixtures acting as epitopes, which are useful as vaccines. The DSP is synthesized based on specific rules regarding the identity and frequency of amino acids that substitute a base or native amino acid of a known epitope. The resulting composition is a mixture of related peptides intended for therapeutic use as a vaccine, particularly against immune evasive infectious agents.
Another notable patent is "Synthesis of directed sequence polymer compositions and antibodies thereof for the treatment of protein conformational disorders." This invention describes a solid-phase synthesis process for directed epitope peptide mixtures that are useful in treating and diagnosing protein conformational disorders. The process is defined by rules regarding amino acid substitutions, leading to a mixture of related peptides for therapeutic applications. Additionally, this invention pertains to generating antibodies using the directed epitope peptide mixtures as antigens, which are valuable in the treatment and diagnostics of protein conformational disorders.
Career Highlights
Throughout his career, Mathers has worked with notable companies such as Declion Pharmaceuticals, Inc. and Declion Holdings LLC. His experience in these organizations has contributed to his expertise in vaccine development and related fields.
Collaborations
Mathers has collaborated with professionals like Dustan Bonnin and Eric Zanelli, enhancing his research and development efforts in the biotechnology sector.
Conclusion
Thomas Mathers is a prominent inventor whose work in vaccine development has the potential to significantly impact public health. His innovative patents reflect a deep understanding of immunology and peptide synthesis, positioning him as a key figure in the fight against infectious diseases.