The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2017

Filed:

Oct. 16, 2008
Applicants:

Dustan Bonnin, Belmont, MA (US);

Eric Zanelli, Sudbury, MA (US);

Jeff Krieger, Newtonville, MA (US);

Thomas Mathers, Boston, MA (US);

Inventors:

Dustan Bonnin, Belmont, MA (US);

Eric Zanelli, Sudbury, MA (US);

Jeff Krieger, Newtonville, MA (US);

Thomas Mathers, Boston, MA (US);

Assignee:

Declion Holdings LLC, Boxford, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/145 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); A61K 39/00 (2006.01); C07K 1/04 (2006.01);
U.S. Cl.
CPC ...
A61K 39/145 (2013.01); A61K 39/12 (2013.01); C07K 1/047 (2013.01); C07K 14/005 (2013.01); A61K 39/00 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01);
Abstract

The instant invention comprises a process of preparing a composition comprising directed sequence polymer (DSP) mixtures that act as epitopes and useful as vaccines, such DSP synthesized according to a set of rules regarding the identity and the frequency of occurrence of amino acids that substitute a base or native amino acid of a known epitope. The resulting composition is a mixture of related peptides for therapeutic use as a vaccine, preferably for infectious agents that are immune evasive.


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