Location History:
- Boston, MA (US) (2006)
- Cambridge, MA (US) (2020)
- Brookline, MA (US) (2004 - 2022)
Company Filing History:
Years Active: 2004-2022
Title: The Innovations of Thomas M. Barnes
Introduction
Thomas M. Barnes is a notable inventor based in Brookline, MA (US), recognized for his significant contributions to the field of biotechnology. He holds a total of 10 patents, showcasing his innovative spirit and dedication to advancing medical science.
Latest Patents
Among his latest patents, Barnes has developed IL-6 antagonists and uses thereof. These antagonists are specifically designed to bind to site II of interleukin-6 (IL-6). The methods disclosed in this patent aim to treat IL-6 related diseases, including conditions affecting the eye, such as diabetic macular edema. Another significant invention by Barnes is a variant serum albumin with improved half-life and other properties. This invention provides methods and materials for creating variant serum albumin amino acid sequences that exhibit enhanced characteristics compared to wild type serum albumin sequences. Furthermore, it includes methods for producing fusion proteins that combine these variant sequences with therapeutic or diagnostic agents, ensuring improved efficacy.
Career Highlights
Throughout his career, Thomas M. Barnes has worked with prominent companies in the biotechnology sector. Notably, he has been associated with Millennium Pharmaceuticals Limited and Eleven Biotherapeutics, Inc. His work in these organizations has contributed to the development of innovative therapies and treatments.
Collaborations
Barnes has collaborated with esteemed colleagues, including John D. Sharp and Michael March Schmidt. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and advancements in research.
Conclusion
Thomas M. Barnes exemplifies the spirit of innovation in biotechnology through his patents and collaborations. His work continues to impact the medical field positively, paving the way for new treatments and therapies.