This inventor holds 4 USPTO granted patents and 1 published patent application. Top assignees: Georgia Tech Research Corporation, University of Virginia Patent Foundation, Emory University. Active years: 2013-2023.
Location History:
- Atlanta, GA (US) (2013 - 2022)
- Crozet, VA (US) (2023)
Company Filing History:
3 out of 2,190 
2 out of 1,043 
1 out of 1,024 
Years Active: 2013-2023
Title: Innovations and Contributions of Thomas Harrison Barker
Introduction
Thomas Harrison Barker is an accomplished inventor based in Atlanta, GA. He has made significant contributions to the field of biomedical engineering, particularly in the modulation of biological activities related to transforming growth factor-beta (TGF-β). With a total of 4 patents, Barker's work has the potential to impact various therapeutic applications.
Latest Patents
Barker's latest patents include innovative methods and compositions for modulating TGF-β biological activity in vertebrate subjects. One notable patent describes how LEMD3 antagonizes TGF-β-driven Smad2/3 transcription in a stiffness-dependent manner in both the nucleus and cytosol. The methods involve administering an effective amount of a substance capable of modulating the activity of LEMD3 to influence TGF-β biological activity. Another significant patent focuses on functionalized microgels with fibrin binding elements. These ultra-low crosslinked microgels, also known as Platelet-like Particles (PLPs), are designed to selectively bind to fibrin under physiological conditions, thereby recapitulating key functions of platelets, including binding and enhancing fibrin clot formation.
Career Highlights
Throughout his career, Thomas Harrison Barker has worked with esteemed organizations such as Georgia Tech Research Corporation and the University of Virginia Patent Foundation. His research has contributed to advancements in the understanding and application of biomaterials in medical settings.
Collaborations
Barker has collaborated with notable colleagues, including Nicole Welsch and Louis Andrew Lyon, to further his research and innovations in the field.
Conclusion
Thomas Harrison Barker's contributions to biomedical engineering through his patents and collaborations highlight his role as a significant inventor in the industry. His work continues to pave the way for advancements in therapeutic applications related to TGF-β and biomaterials.