The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2023
Filed:
Oct. 09, 2019
Applicants:
University of Virginia Patent Foundation, Charlottesville, VA (US);
Emory University, Atlanta, GA (US);
Inventors:
Thomas H. Barker, Crozet, VA (US);
Leandro Moretti, Charlottesville, VA (US);
Dwight M. Chambers, Atlanta, GA (US);
Assignees:
University of Virginia Patent Foundation, Charlottesville, VA (US);
Emory University, Atlanta, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); A61K 38/17 (2006.01); A61K 48/00 (2006.01); A61P 17/00 (2006.01); A61K 31/713 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 31/713 (2013.01); A61K 48/0066 (2013.01); A61P 17/00 (2018.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2320/31 (2013.01);
Abstract
Methods and compositions for modulating transforming growth factor-beta (TGFβ) biological activity in a vertebrate subject in need thereof. The methods involve administering to the vertebrate subject an effective amount of a substance capable of modulating activity of LEMD3 in the vertebrate subject to thereby modulate TGFβ biological activity in the vertebrate subject.