Company Filing History:
Years Active: 2012-2018
Title: Thomas E Lane: Innovator in Monoclonal Antibodies
Introduction
Thomas E Lane is a notable inventor based in Irvine, CA (US). He has made significant contributions to the field of biotechnology, particularly in the development of monoclonal antibodies. With a total of 3 patents, his work has the potential to impact various medical applications.
Latest Patents
One of Lane's latest patents focuses on IP-10 antibodies and their uses. This invention provides isolated monoclonal antibodies, particularly human antibodies, that bind to IP-10 with high affinity. These antibodies inhibit the binding of IP-10 to its receptor, as well as inhibit IP-10-induced calcium flux and cell migration. The patent also includes nucleic acid molecules encoding the antibodies, expression vectors, host cells, and methods for expressing these antibodies. Furthermore, it outlines immunoconjugates, bispecific molecules, and pharmaceutical compositions that comprise the antibodies. The invention also provides methods for inhibiting IP-10 activity, which can be utilized in treating various inflammatory and autoimmune diseases.
Career Highlights
Throughout his career, Thomas E Lane has worked with prominent companies in the biotechnology sector, including Medarex Inc. and Medarex, L.L.C. His expertise in monoclonal antibodies has positioned him as a key figure in the development of innovative therapeutic solutions.
Collaborations
Lane has collaborated with notable professionals in his field, including Shrikant Deshpande and Haichun Huang. These collaborations have contributed to the advancement of his research and the successful development of his patents.
Conclusion
Thomas E Lane's contributions to the field of monoclonal antibodies demonstrate his innovative spirit and dedication to advancing medical science. His patents hold promise for the treatment of various diseases, showcasing the importance of his work in the biotechnology industry.