Location History:
- Frederiksberg, DK (2014)
- Frederiksberg C, DK (2012 - 2018)
Company Filing History:
Years Active: 2012-2018
Title: The Innovations of Thomas Dyrmann Leser in Biotechnology
Introduction
Thomas Dyrmann Leser, an accomplished inventor based in Frederiksberg C, Denmark, has made significant contributions in the field of biotechnology with a total of five patents to his name. His work primarily focuses on innovative solutions aimed at improving health outcomes related to intestinal barrier functions and metabolic disorders.
Latest Patents
Among his latest patents, one noteworthy invention refers to novel isolated strains capable of enhancing the trans-epithelial electrical resistance (TER) of a Caco-2 cell monolayer after just 10 hours of treatment. This increase exceeds 120% of the TER at the start of the treatment. Additionally, these strains have the potential to induce the secretion of over 200 pg/ml of IL-10 and achieve an IL-10:IL-12 ratio greater than one when co-incubated with human PBMC-derived dendritic cells. This invention aims to address various diseases associated with impaired intestinal barrier functions, including inflammatory bowel disease (IBD), insulin resistance, and even mental health conditions like major depressive disorders.
Another innovative patent from Leser focuses on a bacillus composition characterized by rapid germination and outgrowth in bile salts, mimicking a simulated gut environment. This composition serves as a health-promoting supplement in animal feed, enhancing nutrient digestion and availability.
Career Highlights
Thomas Leser is currently affiliated with Chr. Hansen A/S, a company known for its cutting-edge advancements in health and nutrition. His roles have employed his expertise in creating probiotic solutions addressing both human and animal health.
Collaborations
Throughout his career, Thomas Dyrmann Leser has collaborated with notable professionals in his field, including Inge Helmer Knap and Ane Knarreborg. These partnerships have fostered innovation and practical applications of his research in the market.
Conclusion
As an innovator, Thomas Dyrmann Leser exemplifies the spirit of creativity and dedication that drives progress in biotechnology. His patented inventions not only pave the way for advancements in health treatment but also enhance our understanding of the bacterial functions necessary for improved health outcomes.