Thomas Brevig

Title: Thomas Brevig: Innovator in Mammalian Cell Culture

Introduction

Thomas Brevig is a notable inventor based in Jyllinge, Denmark. He has made significant contributions to the field of mammalian cell culture, focusing on methods and compositions that enhance cell attachment and cultivation.

Latest Patents

Brevig holds two patents that reflect his innovative work. His latest patents include a method for creating a surface of a vessel with polystyrene, nitrogen, and oxygen, which facilitates the attachment and cultivation of cells. This invention provides a solid substrate surface that contains at least about 0.5% nitrogen and a sum of oxygen and nitrogen of greater than or equal to 17.2%. The contact angle is at least about 13.9 degrees, and the method does not require a feeder cell layer or an adlayer. Additionally, he has developed methods and surface modified plates for cell attachment, cultivation, and detachment, which also involve treating cells with compounds that inhibit Rho kinase activity.

Career Highlights

Throughout his career, Brevig has worked with prominent companies such as Nunc A/S and Janssen Biotech, Inc. His experience in these organizations has contributed to his expertise in the field of cell culture.

Collaborations

Brevig has collaborated with notable colleagues, including Benjamin Fryer and Shelley Nelson. Their combined efforts have further advanced the research and development in mammalian cell culture.

Conclusion

Thomas Brevig's innovative work in mammalian cell culture has led to significant advancements in the field. His patents and collaborations reflect his commitment to improving methods for cell attachment and cultivation.