Thimma R Rawalpally

Title: Thimma R Rawalpally: Innovator in Pharmaceutical Chemistry

Introduction

Thimma R Rawalpally is a notable inventor based in Florence, SC (US). He has made significant contributions to the field of pharmaceutical chemistry, holding a total of 8 patents. His work focuses on innovative methods for synthesizing compounds that have potential therapeutic applications.

Latest Patents

One of his latest patents is a diazonium-free method to make an indazole intermediate in the synthesis of bicyclic 5-(trifluoromethoxy)-1H-3-indazolecarboxylic acid amides. This invention provides novel methods for preparing 5-(trifluoromethoxy)-1H-3-indazolecarboxylic acid, which serves as a useful precursor for the preparation of bicyclic-5-trifluoromethoxy-1H-indazole-3-carboxylic acid amides. Compounds derived from this method are being studied for their activity as agonists and partial agonists of the nicotinic α-7 receptor. They hold promise for treating various neurological and psychiatric disorders, including Alzheimer's disease and schizophrenia. The methods developed by Rawalpally are particularly useful for scaling up the production of these important compounds.

Career Highlights

Throughout his career, Thimma R Rawalpally has worked with prominent companies in the pharmaceutical industry, including Cabot Corporation and Hoffmann-La Roche Inc. His experience in these organizations has contributed to his expertise in the field and has facilitated his innovative research.

Collaborations

Thimma has collaborated with several professionals in his field, including Robert S Whitehouse and Russell L Warley. These collaborations have likely enriched his research and contributed to the development of his patented methods.

Conclusion

Thimma R Rawalpally is a distinguished inventor whose work in pharmaceutical chemistry has led to significant advancements in the synthesis of therapeutic compounds. His contributions are poised to impact the treatment of critical neurological and psychiatric conditions.