Thilo Enderle

Title: Thilo Enderle: Innovator in Biochemical Detection Methods

Introduction

Thilo Enderle is a notable inventor based in Rheinfelden, Germany. He has made significant contributions to the field of biochemical detection, holding a total of 7 patents. His work focuses on innovative methods for detecting important biochemical compounds, which have implications in various scientific and medical applications.

Latest Patents

One of Thilo Enderle's latest patents is a method for the detection of cAMP and cGMP via a fluorophore and dequencher complex. This invention involves an in vitro method for detecting cAMP or cGMP by contacting a mixture with a complex of a tracer and a dequencher. The tracer is a fluorophore covalently linked to a cAMP quencher, and the method measures changes in fluorescence to determine concentrations of these compounds. Another significant patent is a generic kinase/phosphatase assay with a single readout. This method detects kinase or phosphatase activity by incubating a sample with a substrate molecule and a detection entity, leading to an altered readout of the fluorophore, which indicates the presence of the activity in the sample.

Career Highlights

Thilo Enderle has worked with prominent companies in the industry, including Hoffmann-La Roche Inc. and Carl Zeiss Jena GmbH. His experience in these organizations has contributed to his expertise in biochemical detection methods and innovation.

Collaborations

Throughout his career, Thilo has collaborated with notable colleagues such as Doris Roth and Christof Fattinger. These collaborations have likely enriched his research and development efforts in the field.

Conclusion

Thilo Enderle's contributions to biochemical detection methods through his patents and collaborations highlight his role as an innovator in the scientific community. His work continues to influence advancements in the detection of critical biochemical compounds.