Thierry Lioux

Title: Innovations of Thierry Lioux

Introduction

Thierry Lioux is a prominent inventor based in Balma, France, known for his significant contributions to the field of immunology and biotechnology. With a total of eight patents to his name, he has made remarkable advancements in the development of compounds that can induce cytokine production, which is crucial for immune response.

Latest Patents

One of his latest patents is titled "Pro-cyclic dinucleotides and pro-cyclic dinucleotide conjugates for cytokine induction." This invention provides a Pro-cyclic dinucleotide (Pro-CDN) that includes a STING agonist cyclic dinucleotide coupled to a linker system. The Pro-CDNs can be metabolized at targeted sites into CDNs, allowing them to exert their full immunomodulatory effects. Additionally, the invention includes conjugates where a Pro-CDN is linked to a Biologically Active Molecule (BAM), such as cytotoxic molecules, lipids, proteins, peptides, nucleic acids, sugars, or PRR ligands. The methods related to these compounds aim to treat or prevent diseases like cancers, immunological disorders, or infections. Another notable patent involves cyclic dinucleotide compounds that can be used in the treatment of bacterial infections, viral infections, or cancers.

Career Highlights

Throughout his career, Thierry Lioux has worked with several notable companies, including Invivogen and Kayla Therapeutics. His work has significantly impacted the development of therapeutic strategies in immunology.

Collaborations

Thierry has collaborated with esteemed colleagues such as Fabienne Vernejoul and Gerard Tiraby, contributing to the advancement of research in his field.

Conclusion

Thierry Lioux's innovative work in the field of immunology, particularly through his patents on pro-cyclic dinucleotides, showcases his dedication to advancing medical science. His contributions continue to pave the way for new therapeutic approaches to combat various diseases.