The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 06, 2021
Filed:
Feb. 04, 2020
Applicant:
Kayla Therapeutics, L'Union, FR;
Inventors:
Assignee:
KAYLA THERAPEUTICS, L'Union, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 31/7084 (2006.01);
U.S. Cl.
CPC ...
C07H 21/04 (2013.01); A61K 31/7084 (2013.01); C07H 21/00 (2013.01); C07H 21/02 (2013.01);
Abstract
A cyclic dinucleotide compound of Formula (I): wherein Xis H or F; Xis H or F; at least one among Xand Xis a fluorine atom; Z is OH, OR, SH or SR, wherein: Ris Na or NH, or Ris an enzyme-labile group which provides OH or SH in vivo such as pivaloyloxymethyl; Band Bare bases chosen from Adenine, Hypoxanthine or Guanine, and Bis a different base than Band a pharmaceutically acceptable salt thereof. Pharmaceutical compositions including the cyclic dinucleotide, as well as their use in the treatment of a bacterial infection, a viral infection or a cancer are also described.