Location History:
- Boxmeer, NL (2016)
- Venray, NE (2017)
- Venray, NL (1990 - 2021)
Company Filing History:
Years Active: 1990-2025
Title: Theodorus Jansen: Innovator in Vaccine Development
Introduction
Theodorus Jansen is a notable inventor based in Venray, Netherlands. He has made significant contributions to the field of vaccine development, holding a total of eight patents. His work focuses on creating stable emulsions for bacterial antigens, which are crucial for formulating effective vaccines.
Latest Patents
One of Jansen's latest patents is titled "Stable emulsions of bacterial antigens." This invention is based on the discovery of advantageous properties of a class of known polymeric emulsifiers. The emulsifier class was found to be resistant to degradation by crude bacterial antigen preparations, which previously caused emulsion instability when using prior art emulsifiers. This innovation allows for the formulation of safe, stable, and effective vaccines based on emulsions of oil and water comprising such bacterial antigens. The polymeric emulsifier is a block copolymer with a general formula A-B-A, where component B is the divalent residue of a water-soluble polyalkylene glycol, and component A is the residue of an oil-soluble complex monocarboxylic acid. A preferred emulsifier is PEG-30-di-(polyhydroxystearate).
Another significant patent is the "Combination vaccine for swine." This invention relates to a combination vaccine for swine, which includes non-replicating antigen from porcine circovirus type 2 (PCV2) and live porcine reproductive and respiratory syndrome virus (PRRSV). The combination vaccine is formulated as an oil-in-water emulsion and is adjuvated with squalane and vitamin E-acetate. This combination vaccine has been found to be immunologically effective against all pathogens: PCV2 and PRRSV.
Career Highlights
Throughout his career, Jansen has worked with prominent companies such as Intervet Inc. and Akzo N.V. His expertise in vaccine formulation and emulsification has made him a valuable asset in the field of veterinary medicine.
Collaborations
Jansen has collaborated with notable individuals in his field, including Maarten Hendrik Witvliet and Nicolaas Visser. These collaborations have contributed to the advancement of vaccine technologies and innovations.
Conclusion
Theodorus Jansen's contributions to vaccine development through his innovative patents have significantly impacted the field. His work continues to pave the way for safer and