Theobald Matthias

Title: Theobald Matthias: Innovator in T-Cell Receptor Mutagenesis

Introduction

Theobald Matthias is a prominent inventor based in Mainz, Germany. He has made significant contributions to the field of immunology, particularly in the area of T-cell receptor mutagenesis. His innovative work focuses on developing methods that enhance T-cell responses for cancer therapy.

Latest Patents

Theobald Matthias holds 2 patents related to the rational mutagenesis of α/β T-cell receptors. His latest patents include a method for rational mutagenesis of α/β T-cell receptors and correspondingly mutated MDM2-protein specific α/β T-cell receptors. These inventions relate to the rational mutagenesis of polypeptides that mediate oncogen-specific T-cell responses. They also encompass nucleic acids encoding these receptors and their applications in the therapy, diagnosis, and prevention of cancerous diseases.

Career Highlights

Theobald Matthias is affiliated with Johannes Gutenberg-Universität Mainz, where he conducts his research and development. His work has been instrumental in advancing the understanding of T-cell receptor functionality and its implications for cancer treatment.

Collaborations

One of his notable collaborators is Ralf-Holger Voss, with whom he has worked on various projects related to T-cell receptor mutagenesis.

Conclusion

Theobald Matthias is a key figure in the field of immunology, with a focus on T-cell receptor innovations that hold promise for cancer therapies. His contributions continue to shape the landscape of cancer treatment and research.